Sunday, May 8, 2022 10:00 AM – 10:45 AM ET Exhibit Hall, Workshop Room 1
Exhibitor Workshop: NanoString Technol.
Advances in Spatial Immunology
- Elizabeth Schneider, Ph.D., Spatial Biology: See the Immune Microenvironment in a Whole New Light
- Jacob D. Estes, Ph.D., Prof., Vaccine & Gene Therapy Inst., Affiliate Prof., Dept. of Molecular Microbiology & Immunology, Chief, Div. of Pathobiology and Immunology, Oregon National Primate Res. Ctr. Oregon Hlth. & Sci. Univ., Characterizing and Eliminating the Follicular Dendritic Cell HIV Reservoir
HIV cannot be eradicated by antiretroviral therapies (ART) alone. A comprehensive understanding of all HIV reservoirs with the potential to reignite systemic infection after discontinuation of ART is key to realizing any HIV cure. See how Dr. Estes and his colleagues uncover novel insights into the impact of ART treatment on viral reservoirs in the context of their tissue microenvironments and cellular immune neighborhoods in the non-human primate models using comprehensive spatial profiling strategies. These methods have improved their understanding of the unique FDC-HIV reservoir and provide insights for devising effective treatment approaches as part of a combinatorial HIV cure strategy.