The Bhoj Laboratory, a member of Penn’s Center of Cellular Immunotherapies (CCI), is looking for postdoctoral candidates interested in translational research focused on development of novel T cell immunotherapies. The over goal of the lab is to develop of CAR T cells and other platforms of engineered T cell-based immunotherapies for the treatment of diseases or conditions that are driven by pathogenic immune responses. The overarching premise is centered on the notion that T cell therapies offer several advantages in regard to target cell elimination and immunomodulation where traditional pharmacologic therapies fall short. Existing projects are focused on targeting B cells, plasma cells and T cells that drive autoimmune responses as well as allo-immune responses (e.g. anti-drug antibodies and organ/tissue allograft rejection. Several projects synergistically combine engineered T cell platforms with other biologicals or targeted small molecules for enhanced immune-modulation. Through highly collaborative efforts with academic and industry partners, projects span studies in rodent and NHP models as well as in humans in the form of active clinical trials and correlative studies using patient samples. Competitive candidates will have a strong background in immunology and, ideally, bioinformatics expertise. Penn and CCI offer a rich immunology and immunotherapy environment, with ample access to broad scientific and technique expertise as well as informal and formal mentorship to foster career development. Interested candidates are encouraged to contact the PI to discuss specific projects and opportunities.
Vijay Bhoj, MD PhD
Assistant Professor of Pathology and Laboratory Medicine
Center for Cellular Immunotherapies
Perelman School of Medicine
University of Pennsylvania