Primary Immune Deficiency and Immune Dysregulation

 Sunday, May 8, 2022     10:15 AM – 12:15 PM ET     Oregon Ballroom 201

Primary Immune Deficiency and Immune Dysregulation

Chairs

• Emily M. Mace, Columbia Univ.
• Elissa Deenick, Garvan Inst. of Med. Res.

Speakers

• Ruth J. Napier, Oregon Hlth. and Sci. Univ., T cell intrinsic role for NOD2 in Blau Syndrome
• Marita Bosticardo, NIAID, NIH, Characterization of thymic epithelial cell and thymocyte function and development in patients with thymic defects using scRNAseq profiling
• Zinan Zhang, Harvard Med. Sch., Bi-allelic TTC21A mutations in common variable immunodeficiency patients
• Sukalp Muzumdar, Cold Spring Harbor Lab., A granular view of X-linked chronic granulomatous disease exploiting single-cell transcriptomics
• Julia Bier, Garvan Inst. of Med. Res., Australia, T cell extrinsic mechanics explaining the T cell hyperactivation seen in Activated PI3K δ Syndrome
• Nicolai S. van Oers, Univ. of Texas Southwestern Med. Ctr., 22q11.2 deletion syndrome causes a thymus hypoplasia corrected by mesenchymal cell replacement
• Olivia Bailey, Univ. of Colorado Anschutz Med. Campus, Dissecting the effect of a novel hypomorphic IL2RB mutation on immune dysregulation
• Jose S. Campos Duran, Perelman Sch. of Med., Univ. of Pennsylvania, Dysregulation of CD8⁺ T cell function in the setting of altered cytokine signaling due to inborn errors of immunity