Neonatal Mucosal Immunity

 Monday, May 9, 2022     12:30 PM – 2:30 PM ET     Room B110–112

Neonatal Mucosal Immunity

Chairs

• Kathryn A. Knoop, Mayo Clin.
• Michael A. Silverman, Children’s Hosp. of Philadelphia

Speakers

• Michael A. Silverman, Children’s Hosp. of Philadelphia, Arresting microbiome development limits immune system maturation and resistance to infection
• Katherine Z. Sanidad, Weill Cornell Med., Gut microbiome regulates serotonin production in the neonatal intestine to promote immune tolerance in early life
• Mohammed Amir, Weill Cornell Med., Gut microbiota-reactive IgG regulates gut microbiota development and immunity against enteric pathogens in early life
• Kara G. Greenfield, Mayo Clin., Maternally derived epidermal growth factor mediates protection in neonates from opportunistic intestinal pathogens.
• Ellen Merrick Schill, Washington Univ. in St Louis Sch. of Med., Neonatal antibiotic exposure alters intestinal macrophage frequency and polarization
• Elizabeth Managlia, Ann & Robert H. Lurie Children’s Hosp. of Chicago, CD206⁺MHCII^– macrophages present in the neonatal but not adult intestine do not derive from LysM monocytes and are decreased in experimental Necrotizing Enterocolitis
• Julia A. Brown, Weill Cornell Med. Col., The preterm infant microbiome impairs lung immune responses to respiratory syncytial virus infection