CD4⁺ T Cell Regulation and Responses: Molecular Mechanisms

 Monday, May 9, 2022     8:00 AM – 10:00 AM ET     Room C123–124

CD4⁺ T Cell Regulation and Responses: Molecular Mechanisms

Chairs

• Claire Chougnet, Cincinnati Children’s Med. Ctr.
• Tammy Kielian, Univ. of Nebraska Med. Ctr.

Speakers

• Laura Melissa Atehortua, Cincinnati Children’s Hosp. Med. Ctr., Apolipoprotein E enhance survival of effector memory regulatory T lymphocytes by regulating caspase-dependent apoptosis and lipid metabolism
• Gunjan Kak, Univ. of Nebraska Med. Ctr., Th1 and Th17 cells are critical for limiting the severity of Staphylococcus aureus craniotomy infection
• Ying Ding, Miller Sch. of Med., Univ. of Miami, Blimp1 regulates the growth and function of human regulatory T cells
• Cody Mowery, Gladstone Inst., CRISPR-based functional genomics to decode cis and trans regulation of the CD28, CTLA4, and ICOS costimulatory locus
• Duy Pham, Univ. of Alabama at Birmingham, Sch. of Med., Batf stabilizes the th17 cell developmental program through impairment of stat5-dependent recruitment of Ets1-Runx1 complexes
• Michelle Chu, Indiana Univ. Sch. of Med., TL1A promotes a multi-cytokine Th9 cell phenotype
• Wesley H. Godfrey, Johns Hopkins Univ. Sch. of Med., Inhibition of distinct glycolytic enzymes produces differential effects on CD4 T cell function
• Dean R. Tantin, Univ. of Utah Sch. of Med., Transcription coactivator OCA-B/Pou2af1 is necessary and sufficient to promote T cell-intrinsic CD4 memory