Saturday, May 7, 2022 3:45 PM – 5:45 PM ET Room B110–112
Autoantigen Identification, Autoantigen Specificity, and Central Tolerance
Chairs
- Maria Bettini, Univ. of Utah Sch. of Med.
- Kristin Hogquist, Univ. of Minnesota
Speakers
- Mekha A. Thomas, Johns Hopkins Univ. Sch. of Med., The monocyte cell surface as a novel site of autoantigen generation in Rheumatoid Arthritis
- Mianmian Yin, Univ. of California, San Francisco, Autoantigen specific T-cell receptor induces organ-specific autoimmunity by escaping T cell negative selection
- Alexander J. Dwyer, Univ. of Minnesota, CD4+ T cells targeting a hybrid insulin: chromogranin A self-antigen are necessary and sufficient for autoimmune diabetes initiation
- Yi Jing, Baylor Col. of Med., Insulin specific TCR repertoire analysis reveals functional diversity of Treg TCRs
- Paul Zdinak, Univ. of Pittsburgh Sch. of Med., Profiling transcriptomes, TCR repertoires, and antigenic specificities of islet-infiltrating T cells in non-obese diabetic mice
- Jun Hyung Sin, Univ. of California, San Francisco, Control of medullary thymic epithelial cell development and central tolerance by a zinc finger transcription factor
- Ryan J. Martinez, Univ. of Minnesota, Type III interferon enhances thymic B cell licensing
- Gregory J. Tsay, China Med. Univ., A specific 25-mer peptide from the cysteine protease of P. gingivalis is the epitope of humoral immune response in rheumatoid arthritis